GNEE hot-selling products
ASTM B861 Titanium Alloy Seamless Pipe
Ti-6A1-4V Medical Titanium Alloy Rod
GR7 GR9 Precision Titanium Alloy
Titanium Grade 1 Strip Coil
In pharmaceutical production, equipment frequently comes into contact with inorganic acids such as hydrochloric acid, nitric acid, and sulfuric acid, as well as organic acids and salts, leading to frequent equipment damage due to corrosion. Traditional steel equipment releases iron ions during use, which can contaminate products and compromise drug quality. To address this issue, the pharmaceutical industry began using iron equipment, but this is not the optimal solution, as iron equipment may also corrode under certain conditions.
Vitamin B1, or thiamine hydrochloride, is a hydrochloride drug containing a high concentration of free chloride ions. These ions significantly corrode stainless steel. When stainless steel equipment is used to produce Vitamin B1, corrosive substances may appear in the finished drug in less than six months, severely affecting drug quality.
In contrast, titanium exhibits far superior corrosion resistance compared to stainless steel. The corrosion rate of industrial pure titanium TA3 is extremely low, at only 0.00088 mm/a. As a result, the pharmaceutical industry has begun experimenting with titanium equipment. For example, in the production of Vitamin B1, the use of titanium screw feeders, cyclone separators, vortex bodies, hoppers, discharge pipes, and titanium-lined exhaust hoods increased the qualification rate of Vitamin B1 from a maximum of 95% to 100%. Moreover, no corrosion was observed after more than seven years of using titanium equipment.
Beyond Vitamin B1, titanium is also widely used in the production of other chemically synthesized drugs. For instance, titanium equipment such as titanium heat exchangers, rising film evaporators, titanium nitrification reactors, and titanium centrifuges are employed in the production of drugs like chloramphenicol, metronidazole, and analgin.
In 1980, Wuhan Pharmaceutical Factory pioneered a titanium hanging test by placing titanium sheets inside highly corrosive pyrazolone hydrolysis equipment. After two months of observation, the weight loss of the titanium sheets was almost zero, with no signs of corrosion. This experiment further confirmed the corrosion resistance of titanium in pharmaceutical production.
Subsequently, Wuhan Pharmaceutical Factory and other pharmaceutical companies began widely adopting titanium equipment. A titanium alloy rising film evaporator was manufactured for the chloramphenicol recovery process; titanium centrifugal filters were used in the chloramphenicol centrifugal filtration process; and titanium anchor agitators and titanium filter tanks were applied in the production of the anthelmintic drugs tetramisole and niclofolan.
The use of such titanium equipment not only improved drug qualification rates but also significantly extended equipment service life. For example, in the production of tetramisole, where equipment is exposed to highly corrosive media such as hydrochloric acid and hydrochloride salts, the lifespan of steel equipment is extremely short. After Hanjiang Pharmaceutical Factory adopted titanium filter tanks, the operational results over the years have been remarkable, with the product rate increasing to 100%. Similarly, the titanium anchor agitator used in the production of the veterinary drug niclofolan showed no signs of corrosion, operated normally, and resolved long-standing production challenges.
In summary, the corrosion-resistant application of titanium in pharmaceutical production is of great significance. It not only enhances drug quality and qualification rates but also reduces equipment maintenance and replacement costs, making a substantial contribution to the development of the pharmaceutical industry.
Titanium products provided by GNEE
CNC machined parts
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Machining Equipment |
10 CNC Tapping Center, 260CNC Lathes,200 auto lathe,2 MAZAK five axis CNC, etc. We increase about 10 lathes every month |
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Processing |
Turning, Milling, Drilling, Tapping, Knurling,Wire EDM ,Grinding,Engraving,Knurling,etc. |
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Tolerance |
+/-0.005mm |
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Material Workable |
Copper,Steel, Aluminum, Brass, Stainless Steel, Titanium, Plastics (PEEK,ABS, Teflon,Acrylic , Delrin, PP, PMMA, PC, POM, |
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Surface Treatment |
Nickel Plating, Anodizing, Chorme Plating, Brushing, Polishing, Blacken, Powder coating, Sandblasting, de-buring, |
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Drawing Format |
JPEG, PDF, DWG, DXF, IGS, STEP, CAD |
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MOQ |
No MOQ Required, 1 PC is fine for us. |
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Lead Time |
1-30 days accordingly to your orders. |
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Quality System |
100% inspection before shipment, (CMM, Projector, Gauge and other inspection tools) |
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Size |
Customization |
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Standard |
OEM/ODM |
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FOB Port |
Xiamen,China |
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Pay ment |
50% T/T in advance,50 % before shipment . Accept T/T L/C ,Escrow,paypal,Western Union |
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Packing |
Carton box, wooden case, pallet, etc. |
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Shipping |
By sea,by air,by DHL ,UPS, FedEx, TNT or EMS,ect. |
Titanium tube
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Name |
Titanium Tube & Pipe |
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Material |
Pure Titanium/ Titanium Alloy |
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Standard |
GB/T 3624,GB/T 3625,GB/T 26057
ASTM B337,ASTM B338,ASTM B861,ASTM B862 JIS H 4630 |
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Common Grade |
National standard grades: TA1, TA2, TC4, TA9, TA18, TA10 |
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Length: 50-6000mm or according to customer requirements |
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Outer diameter: 3-300mm or according to customer requirements |
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Wall thickness: 0.2-5.5mm or according to customer requirements |
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Section shape |
Round / Square/Oval/Spiral/Bar |
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Surface |
Bright annealing, Pickling,Polishing |
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Titanium rod
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Material
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Pure titanium and Titanium alloy
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Titanium Grade
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GR1/GR2/GR3/Gr4/GR5/GR7/GR9/GR12/Gr5Eli/Gr23
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Standard
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ASTM B348/ASME SB348, ASTMF67, ASTM F136, ISO-5832-2(3),AMS 4928 etc
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Shape
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Titanium round rod/bar, Titanium square rod/bar,Titanium flat rod/bar
Titanium rectangle rod/bar, Titanium hex rod/bar |
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Diameter
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1-300mm,customizable
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Length
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50mm-6000mm,customizable
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Tolerance
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h6~h13 H10~H13
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Surface
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Bright/Polished/ Machined
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Main Technique
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Hot Forged; Hot Rolled; Cold drawn; Straighten etc
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Heat Treatment
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Usually are Annealled,but Solid Solution & Aging can be also OK
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Material Milling Certificate
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According to. EN 10204.3.1
Including Chemical composition and Mechanical property |
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Application
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Metallurgy, Electronics, Medical, Chemical, Petroleum, Pharmaceutical, aerospace, etc.
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Titanium sheet/plate/strip
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Grade |
GR1,GR2,GR3,GR5,GR6,GR7,GR9,GR11,GR12, etc. |
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Standard |
ASTM B265,ASTM F136,ASTM F67,AMS4928 |
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Size |
0.5-5.0mm x 1000mm x 2000-3500mm (Thickness x Width x Length) |
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Application |
Metallurgy, electronics, machinery, medical treatment, chemical industry, petroleum, medical treatment, aerospace |
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Supply status |
M (Y/ R/ ST) |
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Feature |
High corrosion resistance, low density, good thermal stability |
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Technics |
Hot Forged, Hot Rolled, Cold Rolled, Annealing, Pickling |
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Surface |
Bright, Polished, Pickling, Acid cleaning, Sandblasting |
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Packing |
Export Standard Woodcase |
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Payment terms |
T/T, L/C, D/A, D/P, Escrow, Western Union, PayPal |
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Certificate |
ISO 9001:2008; The third test report; TÜV Rheinland; |
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Delivery time |
7-15days according to the quantity and process of the product |
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Quality and test |
Hardness test, Bending test, Hydrostatic etc. |
Titanium wire
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Wire Shape |
Round Wire |
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Diameter Range(mm) |
0.1-2.5 |
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Standards |
ASTM F2063,GB 24627 |
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Diameter Tolerance |
±0.001mm |
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Surface Finish |
Black Oxidized, Lightly Oxidized, Bright, Ultra Bright, Polished, Clean |
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Delivery Condition |
Straightened superelastic , Cold-worked |
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Supply Form |
Spool wound, Straight |
About Us
GNEE is a trusted exporter of high-purity titanium raw materials. We utilize advanced forging and precision CNC machining to ensure superior product quality. Every shipment is guaranteed through a rigorous pre-shipment inspection process, verifying chemical composition, mechanical properties, and dimensional accuracy to meet global standards.
Email:sale@gneemetal.com
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Enterprise Employees
Cooperating Partner
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